7C69

Crystal structure of beta-glycosides-binding protein of ABC transporter in a closed state bound to sophorose

Summary for 7C69

Entry DOI	10.2210/pdb7c69/pdb
Descriptor	Sugar ABC transporter, periplasmic sugar-binding protein, beta-D-glucopyranose-(1-2)-beta-D-glucopyranose, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	conformational dynamics, substrate-binding protein, induced-fit mechanism, two-step ligand binding, venus fly-trap mechanism, sugar binding protein
Biological source	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Total number of polymer chains	2
Total formula weight	92997.12
Authors	Kanaujia, S.P.,Chandravanshi, M.,Samanta, R. (deposition date: 2020-05-21, release date: 2020-09-16, Last modification date: 2023-11-29)
Primary citation	Chandravanshi, M.,Samanta, R.,Kanaujia, S.P. Conformational Trapping of a beta-Glucosides-Binding Protein Unveils the Selective Two-Step Ligand-Binding Mechanism of ABC Importers. J.Mol.Biol., 432:5711-5734, 2020 Cited by PubMed: 32866452 DOI: 10.1016/j.jmb.2020.08.021 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation