7C2I
Crystal structure of nsp16-nsp10 heterodimer from SARS-CoV-2 in complex with SAM (with additional SAM during crystallization)
Summary for 7C2I
Entry DOI | 10.2210/pdb7c2i/pdb |
Descriptor | 2'-O-methyltransferase, Non-structural protein 10, S-ADENOSYLMETHIONINE, ... (5 entities in total) |
Functional Keywords | 2'-o-methylase, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 2 |
Total formula weight | 50058.96 |
Authors | Lin, S.,Chen, H.,Ye, F.,Chen, Z.M.,Yang, F.L.,Zheng, Y.,Cao, Y.,Qiao, J.X.,Yang, S.Y.,Lu, G.W. (deposition date: 2020-05-07, release date: 2020-05-27, Last modification date: 2023-11-29) |
Primary citation | Lin, S.,Chen, H.,Ye, F.,Chen, Z.,Yang, F.,Zheng, Y.,Cao, Y.,Qiao, J.,Yang, S.,Lu, G. Crystal structure of SARS-CoV-2 nsp10/nsp16 2'-O-methylase and its implication on antiviral drug design. Signal Transduct Target Ther, 5:131-131, 2020 Cited by PubMed: 32728018DOI: 10.1038/s41392-020-00241-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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