7BXA

Crystal structure of PD-1 in complex with tislelizumab Fab

Summary for 7BXA

• Entry DOI: 10.2210/pdb7bxa/pdb
• Descriptor: Programmed cell death protein 1, heavy chain, light chain (3 entities in total)
• Functional Keywords: pd-1, tislelizumab, immune checkpoint, antibody, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 126092.27

Authors

Heo, Y.S.,Lee, S.H.,Lim, H.,Lee, H.T.,Kim, Y.J.,Park, E.B. (deposition date: 2020-04-18, release date: 2020-06-10, Last modification date: 2023-11-29)

• Primary citation: Lee, S.H.,Lee, H.T.,Lim, H.,Kim, Y.,Park, U.B.,Heo, Y.S.; Crystal structure of PD-1 in complex with an antibody-drug tislelizumab used in tumor immune checkpoint therapy.; Biochem.Biophys.Res.Commun., 527:226-231, 2020; PubMed: 32446372; DOI: 10.1016/j.bbrc.2020.04.121

Experimental method

X-RAY DIFFRACTION (3.32 Å)