7BTT

A X-ray cocrystal structure of XMU-MP-5 bound to the ALK kinase domain

Summary for 7BTT

• Entry DOI: 10.2210/pdb7btt/pdb
• Descriptor: ALK tyrosine kinase receptor, 2-(dimethylamino)-1-[5-methoxy-6-[[4-[(2-propan-2-ylsulfonylphenyl)amino]-5H-pyrrolo[3,2-d]pyrimidin-2-yl]amino]-2,3-dihydroindol-1-yl]ethanone (3 entities in total)
• Functional Keywords: kinase, atp binding, inhibitor, complex, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 36497.90

Authors

Yun, C.H.,Zhu, S.J. (deposition date: 2020-04-02, release date: 2021-04-07, Last modification date: 2023-11-29)

• Primary citation: Yun, C.H.,Zhu, S.J.; A X-ray cocrystal structure of XMU-MP-5 bound to the ALK kinase domain; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.86 Å)