7BQ4

X-ray structure of human PPARalpha ligand binding domain-eicosapentaenoic acid (EPA)-SRC1 coactivator peptide co-crystals obtained by delipidation and co-crystallization

Summary for 7BQ4

Entry DOI	10.2210/pdb7bq4/pdb
Descriptor	Peroxisome proliferator-activated receptor alpha, 15-meric peptide from Nuclear receptor coactivator 1, 5,8,11,14,17-EICOSAPENTAENOIC ACID, ... (5 entities in total)
Functional Keywords	nuclear receptor, protein-ligand complex, ppar, transcription
Biological source	Homo sapiens More
Total number of polymer chains	2
Total formula weight	33098.77
Authors	Kamata, S.,Ishikawa, R.,Akahane, M.,Oyama, T.,Ishii, I. (deposition date: 2020-03-23, release date: 2020-11-11, Last modification date: 2023-11-29)
Primary citation	Kamata, S.,Oyama, T.,Saito, K.,Honda, A.,Yamamoto, Y.,Suda, K.,Ishikawa, R.,Itoh, T.,Watanabe, Y.,Shibata, T.,Uchida, K.,Suematsu, M.,Ishii, I. PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates. Iscience, 23:101727-101727, 2020 Cited by PubMed: 33205029 DOI: 10.1016/j.isci.2020.101727 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.62 Å)

Structure validation