7BQ4
X-ray structure of human PPARalpha ligand binding domain-eicosapentaenoic acid (EPA)-SRC1 coactivator peptide co-crystals obtained by delipidation and co-crystallization
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peroxisome proliferator-activated receptor alpha | polymer | 273 | 30856.1 | 1 | UniProt (Q07869) Pfam (PF00104) | Homo sapiens | |
| 2 | B (B) | 15-meric peptide from Nuclear receptor coactivator 1 | polymer | 15 | 1848.2 | 1 | UniProt (Q15788) | Homo sapiens | |
| 3 | C (A) | 5,8,11,14,17-EICOSAPENTAENOIC ACID | non-polymer | 302.5 | 1 | Chemie (EPA) | |||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E (A) | water | water | 18.0 | 103 | Chemie (HOH) |
Sequence modifications
A: 200 - 468 (UniProt: Q07869)
| PDB | External Database | Details |
|---|---|---|
| Gly 196 | - | expression tag |
| Ser 197 | - | expression tag |
| His 198 | - | expression tag |
| Met 199 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32704.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 394.5 | |
| All* | Total formula weight | 33098.8 |
