7BK4

Crystal structure of RXRalpha ligand binding domain in complex with a fragment of the TIF2 coactivator

7BK4 の概要

• エントリーDOI: 10.2210/pdb7bk4/pdb
• 分子名称: Retinoic acid receptor RXR-alpha, Nuclear receptor coactivator 2, 6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)CYCLOPROPYL]PYRIDINE-3-CARBOXYLIC ACID, ... (4 entities in total)
• 機能のキーワード: nuclear receptor, ligand binding domain, coactivator, transcription
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 61395.13

構造登録者

le Maire, A.,Bourguet, W. (登録日: 2021-01-15, 公開日: 2021-08-04, 最終更新日: 2024-01-31)

• 主引用文献: Senicourt, L.,le Maire, A.,Allemand, F.,Carvalho, J.E.,Guee, L.,Germain, P.,Schubert, M.,Bernado, P.,Bourguet, W.,Sibille, N.; Structural Insights into the Interaction of the Intrinsically Disordered Co-activator TIF2 with Retinoic Acid Receptor Heterodimer (RXR/RAR).; J.Mol.Biol., 433:166899-166899, 2021; PubMed: 33647291; DOI: 10.1016/j.jmb.2021.166899

実験手法

X-RAY DIFFRACTION (2.8 Å)