7BG9
The catalytic core lobe of human telomerase in complex with a telomeric DNA substrate
Summary for 7BG9
Entry DOI | 10.2210/pdb7bg9/pdb |
Related | 7BGB |
EMDB information | 12174 12175 12176 12177 |
Descriptor | Telomerase reverse transcriptase,Telomerase reverse transcriptase, DNA (5'-D(P*TP*TP*AP*GP*GP*G)-3'), Histone H2B, ... (5 entities in total) |
Functional Keywords | reverse transcriptase, ribonucleoprotein, complex, dna, rna binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 332366.46 |
Authors | Nguyen, T.H.D.,Ghanim, G.E.,Fountain, A.J.,van Roon, A.M.M.,Rangan, R.,Das, R.,Collins, K. (deposition date: 2021-01-06, release date: 2021-04-28, Last modification date: 2024-05-01) |
Primary citation | Ghanim, G.E.,Fountain, A.J.,van Roon, A.M.,Rangan, R.,Das, R.,Collins, K.,Nguyen, T.H.D. Structure of human telomerase holoenzyme with bound telomeric DNA. Nature, 593:449-453, 2021 Cited by PubMed: 33883742DOI: 10.1038/s41586-021-03415-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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