7BBD

Crystal structure of monoubiquitinated TRIM21 RING (Ub-RING) In complex with ubiquitin charged Ube2N (Ube2N~Ub) and Ube2V2

7BBD の概要

• エントリーDOI: 10.2210/pdb7bbd/pdb
• 分子名称: Polyubiquitin-B,E3 ubiquitin-protein ligase TRIM21, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 variant 2, ... (6 entities in total)
• 機能のキーワード: e3 ubiquitin ligase, e2 conjugating enzyme, ubiquitin chain elongation, ligase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 61198.92

構造登録者

Kiss, L.,Neuhaus, D.,James, L.C. (登録日: 2020-12-17, 公開日: 2021-01-27, 最終更新日: 2024-01-31)

• 主引用文献: Kiss, L.,Clift, D.,Renner, N.,Neuhaus, D.,James, L.C.; RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination.; Nat Commun, 12:1220-1220, 2021; PubMed: 33619271; DOI: 10.1038/s41467-021-21443-6

実験手法

X-RAY DIFFRACTION (2.2 Å)