7B8E

Torpedo californica acetylcholinesterase complexed with Ca+2

Summary for 7B8E

• Entry DOI: 10.2210/pdb7b8e/pdb
• Descriptor: Acetylcholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• Functional Keywords: acetylcholinesterase; assam; differential scanning calorimetry; divalent metal ion; electron paramagnetic resonance; thermal inactivation; torpedo; 4d motif, hydrolase, 3.1.1.7
• Biological source: Tetronarce californica (Pacific electric ray)
• Total number of polymer chains: 1
• Total formula weight: 62219.39

Authors

Silman, I.,Shnyrov, V.L.,Ashani, Y.,Roth, E.,Nicolas, A.,Sussman, J.L. (deposition date: 2020-12-12, release date: 2021-03-17, Last modification date: 2024-01-31)

• Primary citation: Silman, I.,Shnyrov, V.L.,Ashani, Y.,Roth, E.,Nicolas, A.,Sussman, J.L.,Weiner, L.; Torpedo californica acetylcholinesterase is stabilized by binding of a divalent metal ion to a novel and versatile 4D motif.; Protein Sci., 30:966-981, 2021; PubMed: 33686648; DOI: 10.1002/pro.4061

Experimental method

X-RAY DIFFRACTION (2.23 Å)