7B1K

Crystal structure of phosphatidyl serine synthase (PSS) in the closed conformation with bound citrate.

Summary for 7B1K

• Entry DOI: 10.2210/pdb7b1k/pdb
• Descriptor: CDP-diacylglycerol--serine O-phosphatidyltransferase, 5'-O-[(R)-{[(S)-{(2R)-2,3-bis[(9E)-octadec-9-enoyloxy]propoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]cytidine, CALCIUM ION, ... (9 entities in total)
• Functional Keywords: membrane protein, lipid synthase, lipid binding protein
• Biological source: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
• Total number of polymer chains: 2
• Total formula weight: 54462.19

Authors

Yildiz, O.,Centola, M. (deposition date: 2020-11-25, release date: 2021-12-08, Last modification date: 2025-10-01)

• Primary citation: Centola, M.,Betz, H.,Yildiz, O.; Crystal structures of phosphatidyl serine synthase PSS reveal the catalytic mechanism of CDP-DAG alcohol O-phosphatidyl transferases; Nat Commun, 12:6982-, 2021; DOI: 10.1038/s41467-021-27281-w

Experimental method

X-RAY DIFFRACTION (2.2 Å)