7AZN
Structure of mouse AsterC (GramD1c) with a new cholesterol-derived compound
Summary for 7AZN
Entry DOI | 10.2210/pdb7azn/pdb |
Related | 6gqf |
Descriptor | Protein Aster-C, 20alpha-hydroxy-20-(5-methylhexyl)cholesterol, ETHANOL, ... (5 entities in total) |
Functional Keywords | non vesicular cholesterol transport, lipid-binding, endoplasmic reticulum, membrane contact sites, lipid transport |
Biological source | Mus musculus (Mouse) |
Total number of polymer chains | 1 |
Total formula weight | 21618.87 |
Authors | Romartinez-Alonso, B.,Sirvydis, K.,Kim, Y.,Xiao, X.,Jung, M.,Tontonoz, P.,Schwabe, J. (deposition date: 2020-11-16, release date: 2021-01-13, Last modification date: 2024-01-31) |
Primary citation | Xiao, X.,Kim, Y.,Romartinez-Alonso, B.,Sirvydis, K.,Ory, D.S.,Schwabe, J.W.R.,Jung, M.E.,Tontonoz, P. Selective Aster inhibitors distinguish vesicular and nonvesicular sterol transport mechanisms. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 33376205DOI: 10.1073/pnas.2024149118 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.09 Å) |
Structure validation
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