7AY9

Crystal structure of CK2 bound by compound 7

Summary for 7AY9

• Entry DOI: 10.2210/pdb7ay9/pdb
• Descriptor: Casein kinase II subunit alpha, SULFATE ION, 7-(cyclopropylamino)-5-(5-(6-oxo-1,6-dihydropyridin-3-yl)-1-(2-(piperidin-1-yl)ethyl)-1H-1,2,3-triazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile, ... (5 entities in total)
• Functional Keywords: inhibitor, kinase, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 85452.77

Authors

Ferguson, A.,Collie, G.W. (deposition date: 2020-11-11, release date: 2021-11-24)

• Primary citation: Date, M.; Metadynamics simulations of CK2 compound unbinding to understand slow dissociation kinetics.; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.25 Å)