7AY9
Crystal structure of CK2 bound by compound 7
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Casein kinase II subunit alpha | polymer | 342 | 40982.7 | 2 | UniProt (P68400) Pfam (PF00069) In PDB | Homo sapiens (Human) | CK II alpha |
2 | A, B | SULFATE ION | non-polymer | 96.1 | 11 | Chemie (SO4) | |||
3 | A, B | 7-(cyclopropylamino)-5-(5-(6-oxo-1,6-dihydropyridin-3-yl)-1-(2-(piperidin-1-yl)ethyl)-1H-1,2,3-triazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile | non-polymer | 470.5 | 2 | Chemie (S92) | |||
4 | B, A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 24 | Chemie (EDO) | |||
5 | water | water | 18.0 | 460 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 336 (UniProt: P68400)
PDB | External Database | Details |
---|---|---|
His 337 | - | expression tag |
His 338 | - | expression tag |
His 339 | - | expression tag |
His 340 | - | expression tag |
His 341 | - | expression tag |
His 342 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 81965.4 | |
Non-Polymers* | Number of molecules | 37 |
Total formula weight | 3487.4 | |
All* | Total formula weight | 85452.8 |