7AEO

Human ARTD2 in complex with DNA oligonucleotides

Summary for 7AEO

• Entry DOI: 10.2210/pdb7aeo/pdb
• Descriptor: Poly [ADP-ribose] polymerase 2, DNA, SULFATE ION, ... (4 entities in total)
• Functional Keywords: artd2, parp2, dna-damage, dna-repair, adp-ribosylation, dna-binding protein, dna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 66713.29

Authors

Obaji, E.,Maksimainen, M.M.,Galera-Prat, A.,Lehtio, L. (deposition date: 2020-09-17, release date: 2021-05-19, Last modification date: 2024-01-31)

• Primary citation: Obaji, E.,Maksimainen, M.M.,Galera-Prat, A.,Lehtio, L.; Activation of PARP2/ARTD2 by DNA damage induces conformational changes relieving enzyme autoinhibition.; Nat Commun, 12:3479-3479, 2021; PubMed: 34108479; DOI: 10.1038/s41467-021-23800-x

Experimental method

X-RAY DIFFRACTION (2.8 Å)