7AEO

Human ARTD2 in complex with DNA oligonucleotides

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003950	molecular_function	NAD+-protein poly-ADP-ribosyltransferase activity

Functional Information from PROSITE/UniProt

site_id	PS00867
Number of Residues	8
Details	CPSASE_2 Carbamoyl-phosphate synthase subdomain signature 2. LLEANPKA

Chain	Residue	Details
A	LEU498-ALA505

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site_id	PS01121
Number of Residues	15
Details	CASPASE_HIS Caspase family histidine active site. HgsrmSnwVgILSHG

Chain	Residue	Details
A	HIS428-GLY442

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: For poly [ADP-ribose] polymerase activity => ECO:0000305|PubMed:26704974, ECO:0000305|PubMed:30104678, ECO:0000305|PubMed:32028527

Chain	Residue	Details
A	GLU558

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:32028527, ECO:0007744|PDB:6TX3

Chain	Residue	Details
A	HIS428
A	GLY437
A	ARG444
A	SER470

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site_id	SWS_FT_FI3
Number of Residues	1
Details	SITE: Cleavage; by caspase-8 => ECO:0000250|UniProtKB:O88554

Chain	Residue	Details
A	ASP207

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site_id	SWS_FT_FI4
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692

Chain	Residue	Details
A	SER226
A	SER232

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