7A8T

Crystal structure of sarcomeric protein FATZ-1 (mini-FATZ-1 construct) in complex with rod domain of alpha-actinin-2

7A8T の概要

• エントリーDOI: 10.2210/pdb7a8t/pdb
• 関連するPDBエントリー: 7A8U 7ANK
• 分子名称: Alpha-actinin-2, Myozenin-1 (2 entities in total)
• 機能のキーワード: z-disk complex, f-actin crosslinking protein, scaffolding protein, fuzzy complex, structural protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 66670.53

構造登録者

Sponga, A.,Arolas, J.L.,Rodriguez Chamorro, A.,Mlynek, G.,Hollerl, E.,Schreiner, C.,Pedron, M.,Kostan, J.,Ribeiro, E.A.,Djinovic-Carugo, K. (登録日: 2020-08-31, 公開日: 2021-06-30, 最終更新日: 2024-01-31)

• 主引用文献: Sponga, A.,Arolas, J.L.,Schwarz, T.C.,Jeffries, C.M.,Rodriguez Chamorro, A.,Kostan, J.,Ghisleni, A.,Drepper, F.,Polyansky, A.,De Almeida Ribeiro, E.,Pedron, M.,Zawadzka-Kazimierczuk, A.,Mlynek, G.,Peterbauer, T.,Doto, P.,Schreiner, C.,Hollerl, E.,Mateos, B.,Geist, L.,Faulkner, G.,Kozminski, W.,Svergun, D.I.,Warscheid, B.,Zagrovic, B.,Gautel, M.,Konrat, R.,Djinovic-Carugo, K.; Order from disorder in the sarcomere: FATZ forms a fuzzy but tight complex and phase-separated condensates with alpha-actinin.; Sci Adv, 7:-, 2021; PubMed: 34049882; DOI: 10.1126/sciadv.abg7653

実験手法

X-RAY DIFFRACTION (2.69 Å)