7A8T

Crystal structure of sarcomeric protein FATZ-1 (mini-FATZ-1 construct) in complex with rod domain of alpha-actinin-2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Alpha-actinin-2	polymer	476	56211.3	1	UniProt (P35609) Pfam (PF00435) In PDB	Homo sapiens (Human)	Alpha-actinin skeletal muscle isoform 2,F-actin cross-linking protein
2	B	Myozenin-1	polymer	92	10459.2	1	UniProt (Q9NP98) In PDB	Homo sapiens (Human)	Calsarcin-2,Filamin-,actinin- and telethonin-binding protein,Protein FATZ

Sequence modifications

A: 274 - 746 (UniProt: P35609)

PDB	External Database	Details
Gly 271	-	expression tag
Ser 272	-	expression tag
Ser 273	-	expression tag

B: 176 - 263 (UniProt: Q9NP98)

PDB	External Database	Details
Gly 172	-	expression tag
Pro 173	-	expression tag
Ala 174	-	expression tag
Met 175	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	66670.5
All*	Total formula weight	66670.5

*Water molecules are not included.