7A78

Crystal structure of RXR beta LBD in complexes with palmitic acid and GRIP-1 peptide

Summary for 7A78

• Entry DOI: 10.2210/pdb7a78/pdb
• Descriptor: Retinoic acid receptor RXR-beta, Nuclear receptor coactivator 2, PALMITIC ACID, ... (6 entities in total)
• Functional Keywords: rxrb, steroid hormone receptor, inhibitor, lipid binding, fatty acid, structural genomics consortium, sgc, dna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 28787.77

Authors

Chaikuad, A.,Merk, D.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2020-08-27, release date: 2020-10-21, Last modification date: 2024-01-31)

• Primary citation: Chaikuad, A.,Pollinger, J.,Ruhl, M.,Ni, X.,Kilu, W.,Heering, J.,Merk, D.; Comprehensive Set of Tertiary Complex Structures and Palmitic Acid Binding Provide Molecular Insights into Ligand Design for RXR Isoforms.; Int J Mol Sci, 21:-, 2020; PubMed: 33187070; DOI: 10.3390/ijms21228457

Experimental method

X-RAY DIFFRACTION (1.72 Å)