7A5T

Crystal structure of A55E mutant of BlaC from Mycobacterium tuberculosis

Summary for 7A5T

Entry DOI	10.2210/pdb7a5t/pdb
Descriptor	Beta-lactamase, GLYCEROL, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	blac, beta-lactamase, mycobacterium tuberculosis, hydrolase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	29311.63
Authors	Chikunova, A.,Ahmad, M.U.,Perrakis, A.,Ubbink, M. (deposition date: 2020-08-21, release date: 2021-07-07, Last modification date: 2024-01-31)
Primary citation	van Alen, I.,Chikunova, A.,Safeer, A.A.,Ahmad, M.U.D.,Perrakis, A.,Ubbink, M. The G132S Mutation Enhances the Resistance of Mycobacterium tuberculosis beta-Lactamase against Sulbactam. Biochemistry, 60:2236-2245, 2021 Cited by PubMed: 34250791 DOI: 10.1021/acs.biochem.1c00168 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation