7A3V
tRNA-guanine transglycosylase C158S/C281S/Y330C/H333A mutant in complex with 3-hydroxysulfolane
Summary for 7A3V
Entry DOI | 10.2210/pdb7a3v/pdb |
Related | 7A0B |
Descriptor | Queuine tRNA-ribosyltransferase, ZINC ION, GLYCEROL, ... (6 entities in total) |
Functional Keywords | enzyme, disulfide, fragment, transferase |
Biological source | Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821 |
Total number of polymer chains | 1 |
Total formula weight | 43494.61 |
Authors | Nguyen, D.,Heine, A.,Klebe, G. (deposition date: 2020-08-18, release date: 2021-06-16, Last modification date: 2024-01-31) |
Primary citation | Nguyen, D.,Xie, X.,Jakobi, S.,Terwesten, F.,Metz, A.,Nguyen, T.X.P.,Palchykov, V.A.,Heine, A.,Reuter, K.,Klebe, G. Targeting a Cryptic Pocket in a Protein-Protein Contact by Disulfide-Induced Rupture of a Homodimeric Interface. Acs Chem.Biol., 16:1090-1098, 2021 Cited by PubMed: 34081441DOI: 10.1021/acschembio.1c00296 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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