7ZWL
Crystal structure of human STING in complex with 3',3'-c-di-(2'F,2'dAMP)
Summary for 7ZWL
Entry DOI | 10.2210/pdb7zwl/pdb |
Descriptor | Stimulator of interferon protein, Ubiquitin-like protein SMT3, 9-[(1~{R},6~{R},8~{R},9~{S},10~{R},15~{R},17~{R},18~{S})-17-(6-aminopurin-9-yl)-9,18-bis(fluoranyl)-3,12-bis(oxidanyl)-3,12-bis(oxidanylidene)-2,4,11,13-tetraoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadecan-8-yl]purin-6-amine, ... (4 entities in total) |
Functional Keywords | sting, antiviral, activator, antiviral protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 58241.11 |
Authors | |
Primary citation | Klima, M.,Smola, M.,Boura, E. Crystal structure of human STING in complex with 3',3'-c-di-(2'F,2'd To Be Published, |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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