7ZVC
Second crystal form of the mature glutamic-class prolyl-endopeptidase neprosin at 1.85 A resolution.
Summary for 7ZVC
Entry DOI | 10.2210/pdb7zvc/pdb |
Related | 7ZU8 |
Descriptor | C-terminal peptidase, GLY-GLY-GLY-GLY, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total) |
Functional Keywords | glutamic endopeptidase, mature form, coeliac disease therapy, plant protease, pitcher plant, hydrolase |
Biological source | Nepenthes ventricosa x Nepenthes alata More |
Total number of polymer chains | 2 |
Total formula weight | 30119.95 |
Authors | Rodriguez-Banqueri, A.,Eckhard, U.,Del Amo-Maestro, L.,Mendes, S.R.,Guevara, T.,Gomis-Ruth, F.X. (deposition date: 2022-05-14, release date: 2022-08-10, Last modification date: 2024-01-31) |
Primary citation | Del Amo-Maestro, L.,Mendes, S.R.,Rodriguez-Banqueri, A.,Garzon-Flores, L.,Girbal, M.,Rodriguez-Lagunas, M.J.,Guevara, T.,Franch, A.,Perez-Cano, F.J.,Eckhard, U.,Gomis-Ruth, F.X. Molecular and in vivo studies of a glutamate-class prolyl-endopeptidase for coeliac disease therapy. Nat Commun, 13:4446-4446, 2022 Cited by PubMed: 35915115DOI: 10.1038/s41467-022-32215-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
Download full validation report