7ZVC

Second crystal form of the mature glutamic-class prolyl-endopeptidase neprosin at 1.85 A resolution.

Summary for 7ZVC

Entry DOI	10.2210/pdb7zvc/pdb
Related	7ZU8
Descriptor	C-terminal peptidase, GLY-GLY-GLY-GLY, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	glutamic endopeptidase, mature form, coeliac disease therapy, plant protease, pitcher plant, hydrolase
Biological source	Nepenthes ventricosa x Nepenthes alata More
Total number of polymer chains	2
Total formula weight	30119.95
Authors	Rodriguez-Banqueri, A.,Eckhard, U.,Del Amo-Maestro, L.,Mendes, S.R.,Guevara, T.,Gomis-Ruth, F.X. (deposition date: 2022-05-14, release date: 2022-08-10, Last modification date: 2024-01-31)
Primary citation	Del Amo-Maestro, L.,Mendes, S.R.,Rodriguez-Banqueri, A.,Garzon-Flores, L.,Girbal, M.,Rodriguez-Lagunas, M.J.,Guevara, T.,Franch, A.,Perez-Cano, F.J.,Eckhard, U.,Gomis-Ruth, F.X. Molecular and in vivo studies of a glutamate-class prolyl-endopeptidase for coeliac disease therapy. Nat Commun, 13:4446-4446, 2022 Cited by PubMed: 35915115 DOI: 10.1038/s41467-022-32215-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation