7YG5
Structure of human R-type voltage-gated CaV2.3-alpha2/delta1-beta1 channel complex in the topiramate-bound state
Summary for 7YG5
Entry DOI | 10.2210/pdb7yg5/pdb |
EMDB information | 33808 |
Descriptor | Voltage-dependent R-type calcium channel subunit alpha-1E, [(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl sulfamate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total) |
Functional Keywords | voltage-gated calcium channel, cav2.3, complex, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 463732.16 |
Authors | |
Primary citation | Gao, Y.,Bai, Q.,Zhang, X.C.,Zhao, Y. Structural insights into the allosteric effects of the antiepileptic drug topiramate on the Ca V 2.3 channel. Biochem.Biophys.Res.Commun., 725:150271-150271, 2024 Cited by PubMed: 38901222DOI: 10.1016/j.bbrc.2024.150271 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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