7Y72
SARS-CoV-2 spike glycoprotein trimer complexed with Fab fragment of anti-RBD antibody E7 (focused refinement on Fab-RBD interface)
Summary for 7Y72
Entry DOI | 10.2210/pdb7y72/pdb |
EMDB information | 33651 |
Descriptor | Spike glycoprotein, Fab E7 light chain, Fab E7 heavy chain (3 entities in total) |
Functional Keywords | viral protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 312980.14 |
Authors | Chia, W.N.,Tan, C.W.,Tan, A.W.K.,Young, B.,Starr, T.N.,Lopez, E.,Fibriansah, G.,Barr, J.,Cheng, S.,Yeoh, A.Y.Y.,Yap, W.C.,Lim, B.L.,Ng, T.S.,Sia, W.R.,Zhu, F.,Chen, S.,Zhang, J.,Greaney, A.J.,Chen, M.,Au, G.G.,Paradkar, P.,Peiris, M.,Chung, A.W.,Bloom, J.D.,Lye, D.,Lok, S.M.,Wang, L.F. (deposition date: 2022-06-21, release date: 2023-08-02, Last modification date: 2023-08-09) |
Primary citation | Chia, W.N.,Tan, C.W.,Tan, A.W.K.,Young, B.,Starr, T.N.,Lopez, E.,Fibriansah, G.,Barr, J.,Cheng, S.,Yeoh, A.Y.,Yap, W.C.,Lim, B.L.,Ng, T.S.,Sia, W.R.,Zhu, F.,Chen, S.,Zhang, J.,Kwek, M.S.S.,Greaney, A.J.,Chen, M.,Au, G.G.,Paradkar, P.N.,Peiris, M.,Chung, A.W.,Bloom, J.D.,Lye, D.,Lok, S.,Wang, L.F. Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor. Sci Adv, 9:eade3470-eade3470, 2023 Cited by PubMed: 37494438DOI: 10.1126/sciadv.ade3470 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.03 Å) |
Structure validation
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