7Y72
SARS-CoV-2 spike glycoprotein trimer complexed with Fab fragment of anti-RBD antibody E7 (focused refinement on Fab-RBD interface)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | Spike glycoprotein | polymer | 1198 | 132860.2 | 2 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB | Homo sapiens (human) | S glycoprotein,E2,Peplomer protein |
| 2 | P | Fab E7 light chain | polymer | 219 | 23920.7 | 1 | Homo sapiens | ||
| 3 | O | Fab E7 heavy chain | polymer | 221 | 23339.2 | 1 | Homo sapiens |
Sequence modifications
A, C: 16 - 1213 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Ala 683 | Arg 683 | engineered mutation |
| Ala 685 | Arg 685 | engineered mutation |
| Pro 817 | Phe 817 | engineered mutation |
| Pro 892 | Ala 892 | engineered mutation |
| Pro 899 | Ala 899 | engineered mutation |
| Pro 942 | Ala 942 | engineered mutation |
| Pro 986 | Lys 986 | engineered mutation |
| Pro 987 | Val 987 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 312980.1 | |
| All* | Total formula weight | 312980.1 |
