7XJF
Crystal structure of 6MW3211 Fab in complex with CD47
Summary for 7XJF
Entry DOI | 10.2210/pdb7xjf/pdb |
Descriptor | Heavy chain of 6MW3211 Fab, Light chain of 6MW3211 Fab, Leukocyte surface antigen CD47, ... (8 entities in total) |
Functional Keywords | cd47, antibody, fab, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 62587.60 |
Authors | |
Primary citation | Wang, R.,Zhang, C.,Cao, Y.,Wang, J.,Jiao, S.,Zhang, J.,Wang, M.,Tang, P.,Ouyang, Z.,Liang, W.,Mao, Y.,Wang, A.,Li, G.,Zhang, J.,Wang, M.,Wang, S.,Gui, X. Blockade of dual immune checkpoint inhibitory signals with a CD47/PD-L1 bispecific antibody for cancer treatment. Theranostics, 13:148-160, 2023 Cited by PubMed: 36593962DOI: 10.7150/thno.79367 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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