7WI8
Cryo-EM structure of inactive mGlu3 bound to LY341495
Summary for 7WI8
Entry DOI | 10.2210/pdb7wi8/pdb |
EMDB information | 32526 32527 |
Descriptor | Metabotropic glutamate receptor 3, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine (3 entities in total) |
Functional Keywords | glutamate, g protein-coupled receptor, cryo-em, selective ligand, membrane protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 201192.54 |
Authors | Fang, W.,Yang, F.,Xu, C.J.,Ling, S.L.,Lin, L.,Zhou, Y.X.,Sun, W.J.,Wang, X.M.,Liu, P.,Rondard, P.,Pan, S.,Pin, J.P.,Tian, C.L.,Liu, J.F. (deposition date: 2022-01-03, release date: 2022-03-16, Last modification date: 2022-07-20) |
Primary citation | Fang, W.,Yang, F.,Xu, C.,Ling, S.,Lin, L.,Zhou, Y.,Sun, W.,Wang, X.,Liu, P.,Rondard, P.,Shi, P.,Pin, J.P.,Tian, C.,Liu, J. Structural basis of the activation of metabotropic glutamate receptor 3. Cell Res., 32:695-698, 2022 Cited by PubMed: 35236939DOI: 10.1038/s41422-022-00623-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.17 Å) |
Structure validation
Download full validation report