7UOT
Native Lassa glycoprotein in complex with neutralizing antibodies 8.9F and 37.2D
Summary for 7UOT
Entry DOI | 10.2210/pdb7uot/pdb |
EMDB information | 26653 |
Descriptor | Glycoprotein G1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (14 entities in total) |
Functional Keywords | lassa virus, neutralizing antibody, n-linked glycans complex, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Lassa virus More |
Total number of polymer chains | 14 |
Total formula weight | 292032.54 |
Authors | |
Primary citation | Li, H.,Buck, T.,Zandonatti, M.,Yin, J.,Moon-Walker, A.,Fang, J.,Koval, A.,Heinrich, M.L.,Rowland, M.M.,Diaz Avalos, R.,Schendel, S.L.,Parekh, D.,Zyla, D.,Enriquez, A.,Harkins, S.,Sullivan, B.,Smith, V.,Chukwudozie, O.,Watanabe, R.,Robinson, J.E.,Garry, R.F.,Branco, L.M.,Hastie, K.M.,Saphire, E.O. A cocktail of protective antibodies subverts the dense glycan shield of Lassa virus. Sci Transl Med, 14:eabq0991-eabq0991, 2022 Cited by PubMed: 36288283DOI: 10.1126/scitranslmed.abq0991 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.77 Å) |
Structure validation
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