7UOT
Native Lassa glycoprotein in complex with neutralizing antibodies 8.9F and 37.2D
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Glycoprotein G1 | polymer | 259 | 29064.4 | 3 | UniProt (P08669) Pfam (PF00798) In PDB | Lassa virus | |
| 2 | a, b, c | Glycoprotein G2 | polymer | 232 | 26798.0 | 3 | UniProt (P08669) Pfam (PF00798) In PDB | Lassa virus | GP2 |
| 3 | T, P, R | 37.2D light chain (variable domain) | polymer | 105 | 11412.5 | 3 | Homo sapiens | ||
| 4 | S, O, Q | 37.2D heavy chain (variable domain) | polymer | 126 | 13946.5 | 3 | Homo sapiens | ||
| 5 | H | 8.9F heavy chain (variable domain) | polymer | 136 | 15002.5 | 1 | Homo sapiens | ||
| 6 | L | 8.9F light chain (variable domain) | polymer | 109 | 11445.5 | 1 | Homo sapiens | ||
| 7 | Y, l, D, o, p... | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 6 | In PDB GlyTouCan (G15407YE) | |||
| 8 | d, e, h, m, n... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 11 | In PDB GlyTouCan (G42666HT) | |||
| 9 | X, k, G | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 3 | In PDB GlyTouCan (G32152BH) | |||
| 10 | j, q, I, u, V | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1057.0 | 5 | In PDB GlyTouCan (G82348BZ) | |||
| 11 | g, r, M | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 3 | In PDB GlyTouCan (G56014GC) | |||
| 12 | i, t, U | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 3 | In PDB GlyTouCan (G21290RB) | |||
| 13 | Z | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
| 14 | f | alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G11971MR) |
Sequence modifications
a, b, c: 260 - 491 (UniProt: P08669)
| PDB | External Database | Details |
|---|---|---|
| Thr 332 | Met 332 | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 14 |
| Total formula weight | 270112.3 | |
| Branched | Number of molecules | 33 |
| Total formula weight | 21920.3 | |
| All* | Total formula weight | 292032.5 |
