7UOT
Native Lassa glycoprotein in complex with neutralizing antibodies 8.9F and 37.2D
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, I (A, B, C) | Glycoprotein G1 | polymer | 259 | 29064.4 | 3 | UniProt (P08669) Pfam (PF00798) | Lassa virus | |
| 2 | B, F, J (a, b, c) | Glycoprotein G2 | polymer | 232 | 26798.0 | 3 | UniProt (P08669) Pfam (PF00798) | Lassa virus | GP2 |
| 3 | C, G, K (T, P, R) | 37.2D light chain (variable domain) | polymer | 105 | 11412.5 | 3 | Homo sapiens | ||
| 4 | D, H, L (S, O, Q) | 37.2D heavy chain (variable domain) | polymer | 126 | 13946.5 | 3 | Homo sapiens | ||
| 5 | M (H) | 8.9F heavy chain (variable domain) | polymer | 136 | 15002.5 | 1 | Homo sapiens | ||
| 6 | N (L) | 8.9F light chain (variable domain) | polymer | 109 | 11445.5 | 1 | Homo sapiens | ||
| 7 | BA, LA, O, OA, PA... (Y, l, D, o, p...) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 6 | In PDB GlyTouCan (G15407YE) | |||
| 8 | DA, EA, HA, MA, NA... (d, e, h, m, n...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 11 | In PDB GlyTouCan (G42666HT) | |||
| 9 | AA, KA, R (X, k, G) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 3 | In PDB GlyTouCan (G32152BH) | |||
| 10 | JA, QA, S, UA, Y (j, q, I, u, V) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1057.0 | 5 | In PDB GlyTouCan (G82348BZ) | |||
| 11 | GA, RA, V (g, r, M) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 3 | In PDB GlyTouCan (G56014GC) | |||
| 12 | IA, TA, X (i, t, U) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 3 | In PDB GlyTouCan (G21290RB) | |||
| 13 | CA (Z) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
| 14 | FA (f) | alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G11971MR) |
Sequence modifications
a, b, c: 260 - 491 (UniProt: P08669)
| PDB | External Database | Details |
|---|---|---|
| Thr 332 | Met 332 | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 14 |
| Total formula weight | 270112.3 | |
| Branched | Number of molecules | 33 |
| Total formula weight | 21920.3 | |
| All* | Total formula weight | 292032.5 |
