7TUZ
Cryo-EM structure of 7alpha,25-dihydroxycholesterol-bound EBI2/GPR183 in complex with Gi protein
Summary for 7TUZ
Entry DOI | 10.2210/pdb7tuz/pdb |
EMDB information | 26136 |
Descriptor | G-protein coupled receptor 183, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total) |
Functional Keywords | ebi2, gpr183, oxysterol, gpcr, signaling, immunity, immunocyte migration, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 160296.95 |
Authors | |
Primary citation | Chen, H.,Huang, W.,Li, X. Structures of oxysterol sensor EBI2/GPR183, a key regulator of the immune response. Structure, 30:1016-, 2022 Cited by PubMed: 35537452DOI: 10.1016/j.str.2022.04.006 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.12 Å) |
Structure validation
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