7TH2
Single-domain VHH intrabodies neutralize ricin toxin
Summary for 7TH2
Entry DOI | 10.2210/pdb7th2/pdb |
Descriptor | Ricin A chain, VHH antibody, CHLORIDE ION, ... (7 entities in total) |
Functional Keywords | antibody-antigen complex, immune system, immune system-toxin complex, immune system/toxin |
Biological source | Ricinus communis (castor bean) More |
Total number of polymer chains | 4 |
Total formula weight | 90358.89 |
Authors | Rudolph, M.J.,Mantis, N. (deposition date: 2022-01-10, release date: 2022-10-12, Last modification date: 2023-10-18) |
Primary citation | Czajka, T.F.,Vance, D.J.,Davis, S.,Rudolph, M.J.,Mantis, N.J. Single-domain antibodies neutralize ricin toxin intracellularly by blocking access to ribosomal P-stalk proteins. J.Biol.Chem., 298:101742-101742, 2022 Cited by PubMed: 35182523DOI: 10.1016/j.jbc.2022.101742 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.838 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)