7TH2
Single-domain VHH intrabodies neutralize ricin toxin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ricin A chain | polymer | 269 | 30139.0 | 2 | UniProt (P02879) Pfam (PF00161) | Ricinus communis (castor bean) | rRNA N-glycosidase |
| 2 | C, D (C, D) | VHH antibody | polymer | 132 | 14266.8 | 2 | Vicugna pacos | ||
| 3 | AA, BA, DA, E, F... (C, D, A, B) | CHLORIDE ION | non-polymer | 35.5 | 21 | Chemie (CL) | |||
| 4 | N, Z (A, B) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 2 | Chemie (MES) | |||
| 5 | CA, X, Y (C, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | EA, FA (D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 7 | GA, HA, IA, JA (A, B, C, D) | water | water | 18.0 | 542 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 267 (UniProt: P02879)
| PDB | External Database | Details |
|---|---|---|
| Ala -1 | - | expression tag |
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 88811.6 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 1547.3 | |
| All* | Total formula weight | 90358.9 |
