7TFN
Cryo-EM structure of CD4bs antibody Ab1303 in complex with HIV-1 Env trimer BG505 SOSIP.664
Summary for 7TFN
Entry DOI | 10.2210/pdb7tfn/pdb |
EMDB information | 25877 |
Descriptor | Envelope glycoprotein BG505 SOSIP.664 - gp120, 2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose, ... (11 entities in total) |
Functional Keywords | hiv-1 env, neutralizing antibody, cd4 binding site antibody, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 12 |
Total formula weight | 371403.56 |
Authors | Yang, Z.,Bjorkman, P.J. (deposition date: 2022-01-06, release date: 2022-01-19, Last modification date: 2022-02-23) |
Primary citation | Yang, Z.,Dam, K.A.,Bridges, M.D.,Hoffmann, M.A.G.,DeLaitsch, A.T.,Gristick, H.B.,Escolano, A.,Gautam, R.,Martin, M.A.,Nussenzweig, M.C.,Hubbell, W.L.,Bjorkman, P.J. Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer. Nat Commun, 13:732-732, 2022 Cited by PubMed: 35136084DOI: 10.1038/s41467-022-28424-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4 Å) |
Structure validation
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