7SJQ
Ex silico engineering of cystine-dense peptides yielding a potent bispecific T-cell engager
Summary for 7SJQ
Entry DOI | 10.2210/pdb7sjq/pdb |
Descriptor | Programmed cell death 1 ligand 1, Cystine-dense peptide, GLYCEROL, ... (7 entities in total) |
Functional Keywords | pdl1 binder, antitumor protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 19642.37 |
Authors | Rupert, P.B.,Strong, R. (deposition date: 2021-10-18, release date: 2022-06-08, Last modification date: 2023-10-18) |
Primary citation | Crook, Z.R.,Girard, E.J.,Sevilla, G.P.,Brusniak, M.Y.,Rupert, P.B.,Friend, D.J.,Gewe, M.M.,Clarke, M.,Lin, I.,Ruff, R.,Pakiam, F.,Phi, T.D.,Bandaranayake, A.,Correnti, C.E.,Mhyre, A.J.,Nairn, N.W.,Strong, R.K.,Olson, J.M. Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager. Sci Transl Med, 14:eabn0402-eabn0402, 2022 Cited by PubMed: 35584229DOI: 10.1126/scitranslmed.abn0402 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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