7S8H
Structure of Lassa virus glycoprotein bound to Fab 18.5C and Fab 36.1F
Summary for 7S8H
Entry DOI | 10.2210/pdb7s8h/pdb |
Descriptor | Glycoprotein G1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total) |
Functional Keywords | lassa virus, pre-fusion glycoprotein, fab fragment, antibody-mediated neutralization, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Lassa virus More |
Total number of polymer chains | 6 |
Total formula weight | 143631.14 |
Authors | Hastie, K.M.,Enriquez, A.S. (deposition date: 2021-09-17, release date: 2022-06-01, Last modification date: 2023-10-18) |
Primary citation | Enriquez, A.S.,Buck, T.K.,Li, H.,Norris, M.J.,Moon-Walker, A.,Zandonatti, M.A.,Harkins, S.S.,Robinson, J.E.,Branco, L.M.,Garry, R.F.,Saphire, E.O.,Hastie, K.M. Delineating the mechanism of anti-Lassa virus GPC-A neutralizing antibodies. Cell Rep, 39:110841-110841, 2022 Cited by PubMed: 35613585DOI: 10.1016/j.celrep.2022.110841 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
Download full validation report