7RKG

Griffithsin mutant Y28W

Summary for 7RKG

Entry DOI	10.2210/pdb7rkg/pdb
Descriptor	Griffithsin, alpha-D-mannopyranose (3 entities in total)
Functional Keywords	complex, sugar binding protein, hiv inhibitor
Biological source	Griffithsia sp. (strain Q66D336) (Red alga)
Total number of polymer chains	2
Total formula weight	30042.58
Authors	Zhao, G.,Sun, J.,Bewley, C. (deposition date: 2021-07-22, release date: 2022-05-25, Last modification date: 2023-10-25)
Primary citation	Sun, J.,Zhao, G.,Bylund, T.,Lee, M.,Adibhatla, S.,Kwong, P.D.,Chuang, G.Y.,Rawi, R.,Bewley, C.A. C 3 -Symmetric Aromatic Core of Griffithsin Is Essential for Potent Anti-HIV Activity. Acs Chem.Biol., 17:1450-1459, 2022 Cited by PubMed: 35537058 DOI: 10.1021/acschembio.1c00990 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation