7RKG

Griffithsin mutant Y28W

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Griffithsin	polymer	142	14841.1	2	UniProt (P84801)	Griffithsia sp. (strain Q66D336) (Red alga)	GRFT
2	C, D (A, B)	alpha-D-mannopyranose	non-polymer		180.2	2	Chemie (MAN)
3	E, F (A, B)	water	water		18.0	267	Chemie (HOH)

Sequence modifications

A, B: 2 - 121 (UniProt: P84801)

PDB	External Database	Details
Met -20	-	initiating methionine
Gly -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag
Gly 1	-	expression tag
Trp 28	Tyr 28	engineered mutation
Ala 31	Unk 31	variant

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	29682.3
Non-Polymers*	Number of molecules	2
	Total formula weight	360.3
All*	Total formula weight	30042.6

*Water molecules are not included.