7RDW
Crystal Structure of FH1 Fab bound to HXb2 HIV-1 gp120 core
Summary for 7RDW
Entry DOI | 10.2210/pdb7rdw/pdb |
Descriptor | Glycoprotein 120, FH1 Fab Heavy Chain, FH1 Fab Light Chain, ... (10 entities in total) |
Functional Keywords | fh1, vh1-2*02, vrc01, antibody, hiv-1, immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 12 |
Total formula weight | 365285.29 |
Authors | Weidle, C.,Pancera, M. (deposition date: 2021-07-12, release date: 2022-05-25, Last modification date: 2023-10-18) |
Primary citation | Gray, M.D.,Feng, J.,Weidle, C.E.,Cohen, K.W.,Ballweber-Fleming, L.,MacCamy, A.J.,Huynh, C.N.,Trichka, J.J.,Montefiori, D.,Ferrari, G.,Pancera, M.,McElrath, M.J.,Stamatatos, L. Characterization of a vaccine-elicited human antibody with sequence homology to VRC01-class antibodies that binds the C1C2 gp120 domain. Sci Adv, 8:eabm3948-eabm3948, 2022 Cited by PubMed: 35507661DOI: 10.1126/sciadv.abm3948 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.55 Å) |
Structure validation
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