7RDW

Crystal Structure of FH1 Fab bound to HXb2 HIV-1 gp120 core

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0019031	cellular_component	viral envelope
D	0019031	cellular_component	viral envelope
M	0019031	cellular_component	viral envelope
N	0019031	cellular_component	viral envelope

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR194-HIS200
G	TYR194-HIS200
I	TYR192-HIS198

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	40
Details	Region: {"description":"CD4-binding loop","evidences":[{"source":"HAMAP-Rule","id":"MF_04083","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"HAMAP-Rule","id":"MF_04083","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19965434","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26972002","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	20
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"HAMAP-Rule","id":"MF_04083","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11188697","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14981267","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26972002","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9641677","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	12
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"HAMAP-Rule","id":"MF_04083","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"HAMAP-Rule","id":"MF_04083","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11188697","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14981267","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26972002","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"HAMAP-Rule","id":"MF_04083","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11188697","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14981267","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23539181","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26972002","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9641677","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI7
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"HAMAP-Rule","id":"MF_04083","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11188697","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14981267","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9641677","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI8
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"HAMAP-Rule","id":"MF_04083","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21998254","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26972002","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9641677","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI9
Number of Residues	8
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"HAMAP-Rule","id":"MF_04083","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11188697","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26972002","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9641677","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI10
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"HAMAP-Rule","id":"MF_04083","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17301785","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19965434","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2NY7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IDX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IDY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI11
Number of Residues	8
Details	Region: {"description":"V5","evidences":[{"source":"HAMAP-Rule","id":"MF_04083","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI12
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"HAMAP-Rule","id":"MF_04083","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11188697","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14981267","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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