7QDN
Structure of human liver pyruvate kinase from which the B domain has been deleted
Summary for 7QDN
Entry DOI | 10.2210/pdb7qdn/pdb |
Descriptor | Pyruvate kinase PKLR, 1,6-di-O-phosphono-beta-D-fructofuranose, OXALIC ACID, ... (7 entities in total) |
Functional Keywords | pkl, pyruvate kinase, glycolysis, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 8 |
Total formula weight | 390369.40 |
Authors | Lulla, A.,Hyvonen, M. (deposition date: 2021-11-27, release date: 2022-03-30, Last modification date: 2024-01-31) |
Primary citation | Nain-Perez, A.,Foller Fuchtbauer, A.,Haversen, L.,Lulla, A.,Gao, C.,Matic, J.,Monjas, L.,Rodriguez, A.,Brear, P.,Kim, W.,Hyvonen, M.,Boren, J.,Mardinoglu, A.,Uhlen, M.,Grotli, M. Anthraquinone derivatives as ADP-competitive inhibitors of liver pyruvate kinase. Eur.J.Med.Chem., 234:114270-114270, 2022 Cited by PubMed: 35290845DOI: 10.1016/j.ejmech.2022.114270 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.695 Å) |
Structure validation
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