7OPI
Structure of a minimal SF3B core in complex with the inactive modulator spliceostatin E (form I)
Summary for 7OPI
Entry DOI | 10.2210/pdb7opi/pdb |
Related | 5IFE 6EN4 7B91 7B92 7B9C 7OMF |
Descriptor | Splicing factor 3B subunit 3, Splicing factor 3B subunit 5, Splicing factor 3B subunit 1, ... (6 entities in total) |
Functional Keywords | spliceosome, spliceostatin e, splicing inhibitor, splicing |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 4 |
Total formula weight | 219813.54 |
Authors | |
Primary citation | Cretu, C.,Gee, P.,Liu, X.,Agrawal, A.,Nguyen, T.V.,Ghosh, A.K.,Cook, A.,Jurica, M.,Larsen, N.A.,Pena, V. Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors. Nat Commun, 12:4491-4491, 2021 Cited by PubMed: 34301950DOI: 10.1038/s41467-021-24741-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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