7NE0
Structure of the ternary complex between Netrin-1, Repulsive-Guidance Molecule-B (RGMB) and Neogenin
Summary for 7NE0
Entry DOI | 10.2210/pdb7ne0/pdb |
Related PRD ID | PRD_900013 |
Descriptor | Netrin-1, Neogenin, Repulsive Guidance Molecule B, ... (8 entities in total) |
Functional Keywords | cell surface receptor signaling, axon guidance, migration, cancer, growth cone, receptor clustering, netrin, neogenin, repulsive guidance molecule, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 115766.75 |
Authors | Robinson, R.A.,Griffiths, S.C.,van de Haar, L.L.,Malinauskas, T.,van Battum, E.Y.,Zelina, P.,Schwab, R.A.,Karia, D.,Malinauskaite, L.,Brignani, S.,van den Munkhof, M.,Dudukcu, O.,De Ruiter, A.A.,Van den Heuvel, D.M.A.,Bishop, B.,Elegheert, J.,Aricescu, A.R.,Pasterkamp, R.J.,Siebold, C. (deposition date: 2021-02-02, release date: 2021-03-31, Last modification date: 2024-01-31) |
Primary citation | Robinson, R.A.,Griffiths, S.C.,van de Haar, L.L.,Malinauskas, T.,van Battum, E.Y.,Zelina, P.,Schwab, R.A.,Karia, D.,Malinauskaite, L.,Brignani, S.,van den Munkhof, M.H.,Dudukcu, O.,De Ruiter, A.A.,Van den Heuvel, D.M.A.,Bishop, B.,Elegheert, J.,Aricescu, A.R.,Pasterkamp, R.J.,Siebold, C. Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling. Cell, 184:2103-, 2021 Cited by PubMed: 33740419DOI: 10.1016/j.cell.2021.02.045 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.25 Å) |
Structure validation
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