7MXO
CryoEM structure of human NKCC1
Summary for 7MXO
Entry DOI | 10.2210/pdb7mxo/pdb |
EMDB information | 24074 |
Descriptor | Solute carrier family 12 member 2, CHLORIDE ION, POTASSIUM ION (3 entities in total) |
Functional Keywords | sodium, potassium, chloride, co-transporter, ions, human, ctd, tmd, full-length, membrane protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 205185.93 |
Authors | Moseng, M.A. (deposition date: 2021-05-19, release date: 2022-09-28, Last modification date: 2023-05-31) |
Primary citation | Moseng, M.A.,Su, C.C.,Rios, K.,Cui, M.,Lyu, M.,Glaza, P.,Klenotic, P.A.,Delpire, E.,Yu, E.W. Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling. Sci Adv, 8:eabq0952-eabq0952, 2022 Cited by PubMed: 36306358DOI: 10.1126/sciadv.abq0952 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.47 Å) |
Structure validation
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