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7MXO

CryoEM structure of human NKCC1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Solute carrier family 12 member 2polymer923102518.42UniProt (P55011)
Pfam (PF00324)
Pfam (PF03522)
Homo sapiens (human)Basolateral Na-K-Cl symporter,Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2
2C, E
(A, B)
CHLORIDE IONnon-polymer35.52Chemie (CL)
3D, F
(A, B)
POTASSIUM IONnon-polymer39.12Chemie (K)
Sequence modifications
A, B: 284 - 1206 (UniProt: P55011)
PDBExternal DatabaseDetails
Gln 1017Lys 1017conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight205036.8
Non-Polymers*Number of molecules4
Total formula weight149.1
All*Total formula weight205185.9
*Water molecules are not included.

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PDB entries from 2026-01-21

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