7MEM
CryoEM structure of monoclonal Fab 045-09 2B05 binding the lateral patch of influenza virus H1 HA
Summary for 7MEM
Entry DOI | 10.2210/pdb7mem/pdb |
EMDB information | 23792 23793 23794 23795 23796 23797 23798 |
Descriptor | Hemagglutinin HA1 chain, Light chain of monoclonal antibody 045-09 2B05, Heavy chain of monoclonal antibody 045-09 2B05, ... (7 entities in total) |
Functional Keywords | hemagglutinin, monoclonal antibody, influenza virus, immune system, viral protein-immune system complex, viral protein/immune system |
Biological source | Influenza A virus (strain swl A/California/04/2009 H1N1) More |
Total number of polymer chains | 12 |
Total formula weight | 247328.77 |
Authors | |
Primary citation | Guthmiller, J.J.,Han, J.,Li, L.,Freyn, A.W.,Liu, S.T.H.,Stovicek, O.,Stamper, C.T.,Dugan, H.L.,Tepora, M.E.,Utset, H.A.,Bitar, D.J.,Hamel, N.J.,Changrob, S.,Zheng, N.Y.,Huang, M.,Krammer, F.,Nachbagauer, R.,Palese, P.,Ward, A.B.,Wilson, P.C. First exposure to the pandemic H1N1 virus induced broadly neutralizing antibodies targeting hemagglutinin head epitopes. Sci Transl Med, 13:-, 2021 Cited by PubMed: 34078743DOI: 10.1126/scitranslmed.abg4535 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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