7M8W
XFEL crystal structure of the prostaglandin D2 receptor CRTH2 in complex with 15R-methyl-PGD2
Summary for 7M8W
Entry DOI | 10.2210/pdb7m8w/pdb |
Descriptor | Prostaglandin D2 receptor 2, Endolysin chimera, 15R-methyl-prostaglandin D2, SODIUM ION, ... (6 entities in total) |
Functional Keywords | prostaglandin d2 receptor, crth2, 15r-methyl-pgd2, g protein-coupled receptor, gpcr, endolysin fusion, membrane protein, lcp |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 1 |
Total formula weight | 53287.62 |
Authors | Shiriaeva, A.,Han, G.W.,Cherezov, V. (deposition date: 2021-03-30, release date: 2021-08-25, Last modification date: 2023-10-18) |
Primary citation | Liu, H.,Deepak, R.N.V.K.,Shiriaeva, A.,Gati, C.,Batyuk, A.,Hu, H.,Weierstall, U.,Liu, W.,Wang, L.,Cherezov, V.,Fan, H.,Zhang, C. Molecular basis for lipid recognition by the prostaglandin D 2 receptor CRTH2. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 34341104DOI: 10.1073/pnas.2102813118 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.61 Å) |
Structure validation
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