7LAD
Clobetasol propionate bound to CYP3A5
Summary for 7LAD
Entry DOI | 10.2210/pdb7lad/pdb |
Descriptor | Cytochrome P450 3A5, PROTOPORPHYRIN IX CONTAINING FE, Clobetasol propionate, ... (4 entities in total) |
Functional Keywords | cytochrome p450, cyp3a5, membrane protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 56153.22 |
Authors | Buchman, C.D.,Miller, D.,Wang, J.,Jayaraman, S.,Chen, T. (deposition date: 2021-01-06, release date: 2021-10-27, Last modification date: 2023-10-18) |
Primary citation | Wang, J.,Buchman, C.D.,Seetharaman, J.,Miller, D.J.,Huber, A.D.,Wu, J.,Chai, S.C.,Garcia-Maldonado, E.,Wright, W.C.,Chenge, J.,Chen, T. Unraveling the Structural Basis of Selective Inhibition of Human Cytochrome P450 3A5. J.Am.Chem.Soc., 143:18467-18480, 2021 Cited by PubMed: 34648292DOI: 10.1021/jacs.1c07066 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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