7L0F

Monobody 12VC3 Bound to HRAS(WT)

Summary for 7L0F

• Entry DOI: 10.2210/pdb7l0f/pdb
• Descriptor: GTPase HRas, Monobody 12VC3, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: ras gtpase, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 119069.68

Authors

Teng, K.W.,Hattori, T.,Tsai, S.,Koide, S. (deposition date: 2020-12-11, release date: 2021-03-24, Last modification date: 2023-10-18)

• Primary citation: Teng, K.W.,Tsai, S.T.,Hattori, T.,Fedele, C.,Koide, A.,Yang, C.,Hou, X.,Zhang, Y.,Neel, B.G.,O'Bryan, J.P.,Koide, S.; Selective and noncovalent targeting of RAS mutants for inhibition and degradation.; Nat Commun, 12:2656-2656, 2021; PubMed: 33976200; DOI: 10.1038/s41467-021-22969-5

Experimental method

X-RAY DIFFRACTION (1.98 Å)